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Targeting the hypoxia signaling pathway with nanomedicine to reverse immunotherapy resistance

Effects of FAP⁺ cancer-associated fibroblasts on anti-PD-1 immunotherapy and CD4⁺ T cell polarization in gastric cancer

Integrated multi-omics profiling of immune microenvironment and drug resistance signatures for precision prognosis in prostate cancer

ZEB2 upregulation modulates the polarization of TAMs toward the immunosuppressive state in EGFR-TKI-resistant NSCLC

Tumor microenvironment-driven resistance to immunotherapy in non-small cell lung cancer: strategies for Cold-to-Hot tumor transformation

Sophisticated roles of tumor microenvironment in resistance to immune checkpoint blockade therapy in hepatocellular carcinoma

Overcoming drug resistance in castrate-resistant prostate cancer: current mechanisms and emerging therapeutic approaches

Exploring YAP1-related TIME in SCLC: implications for survival and treatment response to immuno-chemotherapy

Integrative multi-omics analysis for identifying novel therapeutic targets and predicting immunotherapy efficacy in lung adenocarcinoma

Mechanisms of immunotherapy resistance in small cell lung cancer

Exploring resistance to immune checkpoint inhibitors and targeted therapies in melanoma

Unlocking the potential of immunotherapy in platinum-resistant ovarian cancer: rationale, challenges, and novel strategies