Topic: Multimodal and Personalized Approaches for Cervical Cancer Treatment

Cervical cancer is the fourth most common malignancy among women worldwide and remains a leading cause of cancer-related mortality, with 85% of cases occurring in developing countries. In recent years, significant progress has been made in treatment strategies, including diverse surgical approaches, fertility-sparing surgeries, advanced radiotherapy techniques, systemic chemotherapy, and novel therapeutics such as anti-angiogenic agents, immune checkpoint inhibitors, and antibody-drug conjugates (ADCs). These advances have broadened treatment options and improved patient outcomes, but they also pose new challenges for developing integrated, multimodal, and personalized treatment strategies. This Special Issue aims to provide a platform for sharing the latest clinical and translational research dedicated to advancing cervical cancer treatment. We welcome submissions in various formats - including original research articles, reviews, meta-analyses, systematic reviews, guidelines, commentaries, editorials, letters to the editor, opinions, and perspectives - that focus on comprehensive, precise, and individualized approaches to the diagnosis, management, and treatment of cervical cancer.

Potential Topics:

Surgery

● Selection and optimizationof surgical approaches for early-stage cervical cancer;

● Advances insentinel lymph node mapping;

● Progress infertility-sparing surgery;

● Perioperative nursing care in cervical cancer surgery.

Radiotherapy

● Advances and clinical applications of radiotherapy incervical cancer;

● Molecular mechanisms of sensitivity and resistance to radiotherapy.

Systemic Therapies

● Immunogenomic insightsand immunotherapy advancements in cervical cancer;

● Neoadjuvant, induction,and adjuvant chemotherapy for locally advanced disease;

● Current and emergingfirst-line therapies;

● Advances in second-line targeted therapies for recurrent and metastatic cervical cancer.

Other

● Clinical implementation and impact of HPV vaccination and cervical precancerous screening;

● Applications, progress,and challenges of artificial intelligence (AI) in diagnosis and treatment;

● Advances in genomic, transcriptomic, proteomic, and metabolomicstudies for personalized treatment;

● Molecular signatures for early detection, prognosis, and therapy selection;

● New technologies incervical cancer treatment.

Cervical cancer, surgery, fertility-sparing surgery, radiotherapy, immunotherapy, targeted therapies, cervical precancerous screening