fig2

Figure 2. Schematic workflow of SELEX. The central schematic delineates the core iterative SELEX cycle (comprising ssDNA library construction, affinity selection, separation/elution, and PCR amplification), alongside several emerging variants such as Cell SELEX, in vivo SELEX, magnetic bead-based SELEX, and microfluidic SELEX. This figure was drawn with BioGDP and is an original work of the authors. BioGDP Agreement Number：GDP20268V0A4A. PCR: Polymerase chain reaction; SELEX: systematic evolution of ligands by exponential enrichment; ssDNA: single-stranded DNA.