fig1

Figure 1. Univariate exposure-response association - estimate (blue line) and 95% credible intervals (gray shaded area) - between urinary heavy metal(loid) concentrations and the outcome (Box-Cox-transformed eGFR), as estimated by the BKMR model for the disease group. The horizontal axis shows the log-transformed urinary heavy metal(loid) concentration (z), and the vertical axis shows the contribution of z to the outcome [h(z)]. eGFR: Estimated glomerular filtration rate; BKMR: Bayesian Kernel Machine Regression.