fig4

From: Integrating dual-transcriptomic and machine learning to establish a miRNA-mRNA-protein triad system for skin wound age estimation

Figure 4. Univariate linear regression models for individual biomarkers in wound age estimation. (A-C) Optimal univariate linear regression models for mmu-miR-15b-5p (A), Rsad2 mRNA (B), and RSAD2 protein (C) within the mmu-miR-15b-5p/Rsad2/RSAD2 triad. The best-fit linear equations and coefficients of determination (R²) were determined within the optimal post-injury time windows; (D-F) Optimal univariate linear regression models for mmu-miR-31-5p (D), Cst6 mRNA (E), and CST6 protein (F) within the mmu-miR-31-5p/Cst6/CST6 triad; (G-I) Optimal univariate linear regression models for mmu-miR-1983 (G), Krt77 mRNA (H), and KRT77 protein (I) within the mmu-miR-1983/Krt77/KRT77 triad.