fig7

Figure 7. McMiA-based flexible neural interface for managing overactive bladder syndrome. (A) Schematics of this implantable neural interface, with images demonstrating its flexibility; (B) Material design of the McMiA-based neural interface, employing a X-GO layer serving as an ion diffusion barrier and a X-BI layer as a conductor to enable bioelectronics for a stable and conformable contact without undesirable electrochemical reactions; (C) In vivo evaluation demonstrated that McMiA-mediated neurostimulation modulates both urine volume and urination interval in an overactive bladder model^[41]. Copyright 2023, American Chemical Society. Statistical significance as stated by ^**P < 0.01 or ^***P < 0.001. McMiA: Multicross-linked membrane–ionogel assembly; X-GO: dopamine-cross-linked graphene oxide; X-BI: genipin-cross-linked biopolymeric ionogel; ECM: extracellular matrix.